Yes - you can use DMARC (Domain-based Message Authentication, Reporting and Conformance) with HubSpot. The domains DMARC policy should have SPF and DKIM both set to "relaxed" alignment, and you'll want to take the following steps:
DMARC is used to tell receivers how to use existing authentication methods like SPF or DKIM to verify the owner of the domain. By default all HubSpot customers are on HubSpot's shared email servers, which are hosted on hubspot.com, so mail won't be in alignment with your own domain's policy by default.
If you are seeing DMARC authentication errors, check out the troubleshooting steps in this article.
Please note that if you purchase a Dedicated IP, our Deliverability Team will configure it to be compatible with your DMARC specifications.